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Ontology Browser

Term:
CAMKK-AMPK signaling cascade (GO:0061762)
Annotations: Rat: (8) Mouse: (9) Human: (8) Chinchilla: (8) Bonobo: (8) Dog: (7) Squirrel: (8) Pig: (7)
Parent Terms Term With Siblings Child Terms
activation of phospholipase A2 activity by calcium-mediated signaling  
calcineurin-mediated signaling +   
calcium-mediated signaling using extracellular calcium source  
calcium-mediated signaling using intracellular calcium source  
CAMKK-AMPK signaling cascade +   
A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.
cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration  
negative regulation of calcium-mediated signaling +   
positive regulation of calcium-mediated signaling +   
positive regulation of cerebellar granule cell migration by calcium 
positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling 
regulation of calcium-mediated signaling +   
regulation of cardiac muscle contraction by calcium ion signaling +   
regulation of skeletal muscle contraction by calcium ion signaling +   

Synonyms
Related Synonyms: stress-activated AMP-activated protein kinase signaling cascade
Definition Sources: GOC:dph, GOC:pad, GOC:PARL, PMID:23010169, PMID:24709372

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.