Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates (GO:0051719)
Annotations: Rat: (3) Mouse: (3) Human: (3) Chinchilla: (0) Bonobo: (3) Dog: (0) Squirrel: (4) Pig: (3) Naked Mole-rat: (3) Green Monkey: (3)
Parent Terms Term With Siblings Child Terms
ATP-dependent DNA (cytosine-5-)-methyltransferase activity 
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates  
DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates  
Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.
DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates  

Synonyms
Xrefs: Reactome:R-HSA-9845308 "DNMT3A:DNMT3L in nascent RNA transcript:MeR-PIWIL4:2'-O-methyl-piRNA:SPOCD1:DNMT3A:DNMT3L methylates cytosine in DNA" ;   reactome:R-HSA-5334097 "DNMT3B:DNMT3L methylates cytosine in DNA" ;   reactome:R-HSA-5334152 "DNMT3A:DNMT3L methylates cytosine in DNA"
Definition Sources: PMID:15689527

paths to the root