Catalysis of the reaction: a 5'-end 2'-deoxyribose-2'-deoxyribonucleotide-DNA = (2E,4S)-4-hydroxypenten-2-al-5-phosphate + a 5'-end 5'-phospho-2'-deoxyribonucleoside-DNA + H+.
ATP-dependent activity, acting on DNA +
carbon-oxygen lyase activity, acting on phosphates +
carbon-oxygen lyase activity, acting on polysaccharides +
carboxymethyloxysuccinate lyase activity
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
cohesin loader activity
cohesin unloader activity
dATP(dGTP)-DNA purinetransferase activity
deoxyribodipyrimidine endonucleosidase activity
DNA alpha-glucosyltransferase activity
DNA beta-glucosyltransferase activity
DNA demethylase activity +
DNA ligase activity +
DNA N-glycosylase activity +
DNA nuclease activity +
DNA photolyase activity +
DNA polymerase activity +
DNA strand exchange activity
DNA topoisomerase activity +
DNA-(apurinic or apyrimidinic site) endonuclease activity +
DNA-deoxyinosine glycosylase activity
DNA-methyltransferase activity +
hydro-lyase activity +
integrase activity +
isochorismate pyruvate lyase activity
O-acetylhomoserine sulfhydrylase activity
phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands