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Ontology Browser
Term:
heparosan-N-sulfate-glucuronate 5-epimerase activity (GO:0047464)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
ADP-glyceromanno-heptose 6-epimerase activity 
aldose 1-epimerase activity  
allulose 6-phosphate 3-epimerase activity 
CDP-abequose epimerase activity 
cellobiose epimerase activity 
chondroitin-glucuronate 5-epimerase activity  
D-ribulose-phosphate 3-epimerase activity  
dTDP-4-dehydrorhamnose 3,5-epimerase activity 
GDP-mannose 3,5-epimerase activity  
glucose-6-phosphate 1-epimerase activity 
heparosan-N-sulfate-glucuronate 5-epimerase activity  
Catalysis of the reaction: (heparosan-N-sulfate)(n) = (heparan-N-sulfate)(n). Converts D-glucosyluronate residues to L-iduronate residues.
L-fucose mutarotase activity  
L-rhamnose mutarotase activity 
L-ribulose-5-phosphate 3-epimerase activity 
L-ribulose-phosphate 4-epimerase activity 
maltose epimerase activity 
N-acylglucosamine 2-epimerase activity  
N-acylglucosamine-6-phosphate 2-epimerase activity 
UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity 
UDP-arabinose 4-epimerase activity 
UDP-glucosamine 4-epimerase activity 
UDP-glucose 4-epimerase activity  
UDP-glucuronate 4-epimerase activity 
UDP-glucuronate 5'-epimerase activity  
UDP-N-acetylglucosamine 2-epimerase activity  
UDP-N-acetylglucosamine 4-epimerase activity  

Synonyms
Exact Synonyms: heparosan-N-sulphate-glucuronate 5-epimerase activity
Related Synonyms: C-5 uronosyl epimerase activity ;   D-glucuronyl C-5 epimerase activity ;   heparosan epimerase activity ;   heparosan-N-sulfate-D-glucuronosyl 5-epimerase activity ;   poly[(1,4)-beta-D-glucuronosyl-(1,4)-N-sulfo-alpha-D-glucosaminyl] glucurono-5-epimerase activity ;   polyglucuronate epimerase activity
Xrefs: EC:5.1.3.17 ;   MetaCyc:5.1.3.17-RXN ;   RHEA:20197 ;   Reactome:R-HSA-2024100 "GLCE epimerises GlcA to IdoA" ;   Reactome:R-HSA-2076371 "GLCE epimerises more GlcA to IdoA as sulfate content rises"
Definition Sources: EC:5.1.3.17, MetaCyc:5.1.3.17-RXN

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