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Ontology Browser

Term:
negative regulation of MAPK cascade (GO:0043409)
Annotations: Rat: (205) Mouse: (212) Human: (216) Chinchilla: (174) Bonobo: (180) Dog: (205) Squirrel: (177) Pig: (202)
Parent Terms Term With Siblings Child Terms
ERK1 and ERK2 cascade +   
ERK5 cascade +   
negative regulation of calcium-mediated signaling +   
negative regulation of cAMP-mediated signaling  
negative regulation of cell cycle checkpoint +   
negative regulation of cGMP-mediated signaling  
negative regulation of hippo signaling  
negative regulation of I-kappaB kinase/NF-kappaB signaling +   
negative regulation of intrinsic apoptotic signaling pathway +   
negative regulation of MAPK cascade +   
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
negative regulation of NIK/NF-kappaB signaling  
negative regulation of nitric oxide mediated signal transduction  
negative regulation of osmosensory signaling pathway +  
negative regulation of phosphatidylinositol 3-kinase signaling  
negative regulation of phosphorelay signal transduction system +  
negative regulation of protein kinase B signaling  
negative regulation of protein kinase C signaling  
negative regulation of protein kinase D signaling 
negative regulation of signal transduction by p53 class mediator +   
negative regulation of SMAD protein signal transduction  
negative regulation of small GTPase mediated signal transduction +   
negative regulation of stress-activated protein kinase signaling cascade +   
negative regulation of TOR signaling +   
pheromone response MAPK cascade +  
positive regulation of MAPK cascade +   
regulation of ERK1 and ERK2 cascade +   
regulation of ERK5 cascade +   
regulation of MAPK cascade +   
regulation of stress-activated MAPK cascade +   
stress-activated MAPK cascade +   

Synonyms
Exact Synonyms: down regulation of MAPK cascade ;   down regulation of MAPKKK cascade ;   downregulation of MAPK cascade ;   downregulation of MAPKKK cascade ;   negative regulation of MAP kinase cascade ;   negative regulation of MAP kinase kinase kinase cascade ;   negative regulation of MAPKKK cascade ;   negative regulation of mitogen activated protein kinase cascade ;   negative regulation of mitogen activated protein kinase kinase kinase cascade
Narrow Synonyms: inhibition of MAPK cascade ;   inhibition of MAPKKK cascade
Definition Sources: GOC:go_curators

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