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Ontology Browser
Term:
cross-receptor inhibition within G protein-coupled receptor heterodimer (GO:0038041)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
cross-receptor inhibition within G protein-coupled receptor heterodimer 
Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.
negative regulation of acetylcholine-gated cation channel activity 
negative regulation of advanced glycation end-product receptor activity 
negative regulation of AMPA receptor activity  
negative regulation of brain-derived neurotrophic factor-activated receptor activity 
negative regulation of corticotropin-releasing hormone receptor activity 
negative regulation of epidermal growth factor-activated receptor activity 
negative regulation of G protein-coupled receptor signaling pathway +   
negative regulation of GABA-A receptor activity 
negative regulation of nerve growth factor receptor activity 
negative regulation of NMDA glutamate receptor activity  
negative regulation of osmolarity-sensing cation channel activity 
negative regulation of proteinase activated receptor activity 
positive regulation of G protein-coupled receptor signaling pathway +   
protein kinase C deactivation  
regulation of adenosine receptor signaling pathway +   
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +   
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway  
regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +   
regulation of angiotensin-activated signaling pathway +   
regulation of chemokine-mediated signaling pathway +   
regulation of endocannabinoid signaling pathway  
regulation of G protein-coupled receptor internalization +   
regulation of octopamine or tyramine signaling pathway +  
regulation of opioid receptor signaling pathway +   
regulation of opsin-mediated signaling pathway +   
regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +   
regulation of thrombin-activated receptor signaling pathway +   

Synonyms
Definition Sources: GOC:al, GOC:bf, PMID:15979374

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