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Ontology Browser

Term:
cross-receptor inhibition within G protein-coupled receptor heterodimer (GO:0038041)
Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (2) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
cross-receptor inhibition within G protein-coupled receptor heterodimer  
Inhibition of one protomer of a G protein-coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.
modulation by symbiont of host G protein-coupled receptor signal transduction +  
negative regulation of acetylcholine-gated cation channel activity  
negative regulation of advanced glycation end-product receptor activity  
negative regulation of AMPA receptor activity 
negative regulation of beta1-adrenergic receptor activity 
negative regulation of brain-derived neurotrophic factor-activated receptor activity  
negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway 
negative regulation of corticotropin-releasing hormone receptor activity  
negative regulation of epidermal growth factor-activated receptor activity  
negative regulation of G protein-coupled receptor signaling pathway +   
negative regulation of GABA-A receptor activity 
negative regulation of nerve growth factor receptor activity 
negative regulation of NMDA glutamate receptor activity  
negative regulation of osmolarity-sensing cation channel activity 
negative regulation of proteinase activated receptor activity 
positive regulation of G protein-coupled receptor signaling pathway +   
protein kinase C deactivation  
regulation of adenosine receptor signaling pathway +   
regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +   
regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway +   
regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway +   
regulation of angiotensin-activated signaling pathway +   
regulation of endocannabinoid signaling pathway  
regulation of G protein-coupled receptor internalization +   
regulation of octopamine or tyramine signaling pathway +  
regulation of opioid receptor signaling pathway +   
regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +   
regulation of rhodopsin mediated signaling pathway +   
regulation of thrombin-activated receptor signaling pathway +   

Synonyms
Definition Sources: GOC:al, GOC:bf, PMID:15979374

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