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Ontology Browser

Term:
RNA N6-methyladenosine methyltransferase complex (GO:0036396)
Annotations: Rat: (8) Mouse: (8) Human: (8) Chinchilla: (8) Bonobo: (8) Dog: (8) Squirrel: (8) Pig: (8)
Parent Terms Term With Siblings Child Terms
apolipoprotein B mRNA editing enzyme complex  
DNA methyltransferase complex 
eRF1 methyltransferase complex  
histone methyltransferase complex +   
methanol-CoM methyltransferase complex 
methylosome  
methylthiol:coenzyme M methyltransferase complex 
mitochondrial mRNA editing complex 
mRNA cap methyltransferase complex  
plastid mRNA editing complex 
RNA N6-methyladenosine methyltransferase complex  
A RNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and associated components WTAP, ZC3H13, VIRMA, CBLL1/HAKAI and in some cases of RBM15 (RBM15 or RBM15B).
tRNA methyltransferase complex +   

Synonyms
Exact Synonyms: Mum2, Ime4, and Slz1 complex ;   WMM complex
Related Synonyms: METTL3-METTL14-WTAP methyltransferase complex ;   MIS complex ;   m(6)A writer complex ;   m6A methyltransferase complex
Definition Sources: GOC:dgf, GOC:sp, PMID:22685417, PMID:24316715, PMID:24407421, PMID:29507755, PMID:29535189, PMID:29547716

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