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7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity 
[acyl-carrier-protein] phosphodiesterase activity 
alkylglycerophosphoethanolamine phosphodiesterase activity  
cardiolipin hydrolase activity  
catalytic activity, acting on a rRNA +   
catalytic activity, acting on a tRNA +   
CMP-N-acylneuraminate phosphodiesterase activity 
cyclic-guanylate-specific phosphodiesterase activity 
cyclic-nucleotide phosphodiesterase activity +   
DNA/RNA helicase activity +   
dolichylphosphate-glucose phosphodiesterase activity 
dolichylphosphate-mannose phosphodiesterase activity 
first spliceosomal transesterification activity 
glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity 
glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity 
glycerophosphocholine cholinephosphodiesterase activity  
glycerophosphocholine phosphodiesterase activity  
glycerophosphodiester phosphodiesterase activity  
glycerophosphoinositol glycerophosphodiesterase activity  
glycerophosphoinositol inositolphosphodiesterase activity  
GPI-mannose ethanolamine phosphate phosphodiesterase activity  
mRNA 5'-diphosphatase activity  
mRNA 5'-triphosphate monophosphatase activity  
N-acylphosphatidylethanolamine-specific phospholipase D activity  
oxidative RNA demethylase activity +   
phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands  
phosphodiesterase I activity  
phospholipase C activity +   
phospholipase D activity +   
phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase activity 
phosphoribosyl 1,2-cyclic phosphate phosphodiesterase activity 
protein adenylylhydrolase activity  
RNA 2',3'-cyclic 3'-phosphodiesterase activity 
RNA glycosylase activity +  
RNA guanylyltransferase activity +   
RNA helicase activity +   
RNA ligase activity +   
RNA methyltransferase activity +   
RNA NAD+-cap (NAD+-forming) hydrolase activity  
RNA NAD-cap (NMN-forming) hydrolase activity  
RNA nuclease activity +   
RNA polymerase activity +   
RNA topoisomerase activity  
RNA uridylyltransferase activity  
RNA-3'-phosphate cyclase activity  
rRNA pseudouridine synthase activity +  
second spliceosomal transesterification activity  
serine-ethanolaminephosphate phosphodiesterase activity 
snRNA pseudouridine synthase activity 
sphingomyelin phosphodiesterase activity +   
sphingomyelin phosphodiesterase D activity  
template-free RNA nucleotidyltransferase  
tyrosyl-DNA phosphodiesterase activity +   
tyrosyl-RNA phosphodiesterase activity  
Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.

Synonyms
Exact Synonyms: VPg unlinkase activity ;   Y-pUpN PDE activity ;   unlinkase activity ;   uridylylpolynucleotide-(5' P->O)- tyrosine phosphodiesterase activity
Definition Sources: GOC:bf, GOC:sp, PMID:21408223, PMID:22908287

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