Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
RNA capping +     
RNA methylation +     
7-methylguanosine cap hypermethylation  
Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.
7-methylguanosine RNA capping +   
RNA (guanine-N7)-methylation +   
rRNA methylation +   
snoRNA 2,2,7-trimethylguanosine (TMG) capping +  
snRNA 2,2,7-trimethylguanosine (TMG) capping 
snRNA methylation +   
tRNA methylation +   

Synonyms
Exact Synonyms: 2,2,7-trimethylguanosine cap formation ;   TMG cap formation ;   conversion of m(7)G to m(3)G ;   m(7)G cap hypermethylation
Narrow Synonyms: hypermethylation of snRNA cap ;   hypermethylation of snoRNA cap ;   snRNA capping ;   snoRNA capping
Definition Sources: GOC:bf, GOC:BHF, GOC:krc, GOC:mah, GOC:rl, PMID:11983179, PMID:18775984

paths to the root