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Ontology Browser

Parent Terms Term With Siblings Child Terms
homodimeric serine palmitoyltransferase complex 
SPOTS complex  
A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.

Narrow Synonyms: serine palmitoyltransferase, Orm1/2, Tsc3 and Sac1 complex
Definition Sources: PMID:20182505

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