The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
nucleoside bisphosphate catabolic process +
nucleoside diphosphate biosynthetic process +
nucleoside monophosphate biosynthetic process +
nucleoside triphosphate biosynthetic process +
nucleotide biosynthetic process +
purine nucleoside bisphosphate metabolic process +