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AMPA glutamate receptor complex (GO:0032281)
Annotations: Rat: (30) Mouse: (30) Human: (28) Chinchilla: (28) Bonobo: (28) Dog: (28) Squirrel: (28) Pig: (27)
Parent Terms Term With Siblings Child Terms
AMPA glutamate receptor complex  
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
calcium channel complex +   
intracellular cyclic nucleotide activated cation channel complex  
kainate selective glutamate receptor complex  
NMDA selective glutamate receptor complex  
potassium channel complex +   
serotonin-activated cation-selective channel complex  
sodium channel complex +   

Exact Synonyms: AMPA-selective glutamate receptor complex ;   alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
Related Synonyms: AMPA receptor
Definition Sources: GOC:ef

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.