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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
clathrin-dependent endocytosis +   
endocytic heme import into cell +   
endocytic iron import into cell  
low-density lipoprotein receptor particle metabolic process +   
negative regulation of receptor-mediated endocytosis +   
neurotransmitter receptor metabolic process +   
positive regulation of receptor-mediated endocytosis +   
receptor biosynthetic process +   
receptor catabolic process +   
receptor internalization +   
A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
receptor recycling +   
receptor-mediated endocytosis involved in cholesterol transport +   
receptor-mediated endocytosis of virus by host cell +   
regulation of receptor-mediated endocytosis +   

Synonyms
Definition Sources: GOC:bf, GOC:mah, GOC:signaling, PMID:15006537, PMID:19643732

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.