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Ontology Browser

Term:
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031586)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0)
Parent Terms Term With Siblings Child Terms
negative regulation of acetylcholine-gated cation channel activity  
negative regulation of acid-sensing ion channel activity  
negative regulation of AMPA receptor activity 
negative regulation of ATPase-coupled calcium transmembrane transporter activity  
negative regulation of calcineurin-mediated signaling +   
negative regulation of calcium:sodium antiporter activity  
negative regulation of CAMKK-AMPK signaling cascade  
negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
negative regulation of large conductance calcium-activated potassium channel activity 
negative regulation of NMDA glutamate receptor activity  
negative regulation of osmolarity-sensing cation channel activity 
negative regulation of proton-transporting ATP synthase activity, rotational mechanism 
negative regulation of ryanodine-sensitive calcium-release channel activity  
negative regulation of store-operated calcium channel activity  
negative regulation of voltage-gated calcium channel activity +   
negative regulation of voltage-gated potassium channel activity +   
negative regulation of voltage-gated sodium channel activity 
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity  

Synonyms
Exact Synonyms: down regulation of IP3 receptor activity ;   downregulation of IP3 receptor activity ;   negative regulation of inositol 1,4,5-trisphosphate receptor activity
Narrow Synonyms: inhibition of IP3 receptor activity
Related Synonyms: negative regulation of IP3 receptor activity
Definition Sources: GOC:dph, GOC:mah, GOC:signaling

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.