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Term:
endoplasmic reticulum unfolded protein response (GO:0030968)
Annotations: Rat: (72) Mouse: (71) Human: (133) Chinchilla: (55) Bonobo: (57) Dog: (70) Squirrel: (54) Pig: (70)
Parent Terms Term With Siblings Child Terms
apoptotic signaling pathway +   
bile acid signaling pathway +   
calmodulin dependent kinase signaling pathway +   
carbohydrate mediated signaling +   
cell surface receptor signaling pathway +   
chloroplast-nucleus signaling pathway 
dopamine receptor signaling pathway +   
endoplasmic reticulum stress-induced pre-emptive quality control  
endoplasmic reticulum unfolded protein response +   
The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
ER overload response +   
ER-nucleus signaling pathway +   
ERAD pathway +   
extracellular ATP signaling 
G protein-coupled receptor signaling pathway +   
hormone-mediated signaling pathway +   
hydrogen peroxide mediated signaling pathway +  
hypoxia-inducible factor-1alpha signaling pathway +   
immune response-regulating signaling pathway +   
intracellular receptor signaling pathway +   
intracellular signal transduction +   
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress +   
ligand-gated ion channel signaling pathway +  
lipoprotein particle mediated signaling +   
mitochondria-nucleus signaling pathway  
mitochondrial unfolded protein response +   
necroptotic signaling pathway  
negative regulation of response to endoplasmic reticulum stress +   
negative regulation of signal transduction +   
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress  
neuronal signal transduction +   
osmosensory signaling pathway +   
pattern recognition receptor signaling pathway +   
peptidoglycan recognition protein signaling pathway +  
phototransduction +   
positive regulation of response to endoplasmic reticulum stress +   
positive regulation of signal transduction +   
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress  
postsynaptic signal transduction +   
presynaptic signal transduction +   
red or far-red light signaling pathway +   
regulation of blood pressure by chemoreceptor signaling pathway 
regulation of floral organ abscission by signal transduction +  
regulation of response to endoplasmic reticulum stress +   
regulation of signal transduction +   
regulation of translation in response to endoplasmic reticulum stress +   
response to manganese-induced endoplasmic reticulum stress  
salicylic acid mediated signaling pathway +  
serotonin receptor signaling pathway +   
signal transduction by conformational transition 
signal transduction by protein phosphorylation +   
signal transduction in absence of ligand +   
signal transduction involved in cellular response to ammonium ion 
signal transduction involved in filamentous growth 
signal transduction involved in morphogenesis checkpoint 
signal transduction involved in positive regulation of conjugation with cellular fusion +  
signal transduction involved in regulation of gene expression  
SMAD protein signal transduction +   
sphingolipid mediated signaling pathway +   

Synonyms
Exact Synonyms: ER unfolded protein response ;   erUPR
Related Synonyms: SREBP-mediated signalling pathway
Definition Sources: GOC:mah, PMID:12042763

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.