The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
arginine catabolic process to glutamate
cyclization of glutamine involved in intein-mediated protein splicing
D-glutamate metabolic process
D-glutamine metabolic process
glutamate biosynthetic process +
glutamate catabolic process +
glutamine biosynthetic process +
glutamine catabolic process
L-histidine catabolic process to glutamate and formamide
L-histidine catabolic process to glutamate and formate
negative regulation of glutamate metabolic process +
negative regulation of nitrogen utilization +
positive regulation of glutamate metabolic process +
positive regulation of nitrogen utilization +
proline catabolic process to glutamate +
regulation of glutamate metabolic process +
regulation of nitrogen utilization +
tetrapyrrole biosynthetic process from glutamate +