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Ontology Browser
Term:
oxidative phosphorylation uncoupler activity (GO:0017077)
Annotations: Rat: (5) Mouse: (5) Human: (5) Chinchilla: (4) Bonobo: (4) Dog: (5) Squirrel: (4) Pig: (5) Naked Mole-rat: (4) Green Monkey: (4)
Parent Terms Term With Siblings Child Terms
3-hydroxyphenyl propanoate transmembrane transporter activity +  
acetate ester transmembrane transporter activity +   
active transmembrane transporter activity +   
alcohol transmembrane transporter activity +   
alkane transmembrane transporter activity 
amide transmembrane transporter activity +   
amine transmembrane transporter activity +   
amino acid transmembrane transporter activity +   
arsenate ion transmembrane transporter activity +  
auxin transmembrane transporter activity +  
azole transmembrane transporter activity +   
bicyclomycin transmembrane transporter activity 
biopterin transmembrane transporter activity 
carbohydrate derivative transmembrane transporter activity +   
carbohydrate transmembrane transporter activity +   
carbon dioxide transmembrane transporter activity  
chlorophyll catabolite transmembrane transporter activity 
cyanate transmembrane transporter activity +  
efflux transmembrane transporter activity +   
ergothioneine transmembrane transporter activity 
ferric triacetylfusarinine C transmembrane transporter activity +  
heme transmembrane transporter activity +   
inorganic molecular entity transmembrane transporter activity +   
iron chelate transmembrane transporter activity +  
lipid transmembrane transporter activity +   
lipo-chitin oligosaccharide transmembrane transporter activity +  
lipoate transmembrane transporter activity 
macromolecule transmembrane transporter activity +   
mevalonate transmembrane transporter activity  
mobile ion carrier activity 
modified amino acid transmembrane transporter activity +   
monoatomic ion transmembrane transporter activity +   
neurotransmitter transmembrane transporter activity +   
nucleobase transmembrane transporter activity +   
nucleobase-containing compound transmembrane transporter activity +   
organic acid transmembrane transporter activity +   
organic anion transmembrane transporter activity +   
organic cation transmembrane transporter activity +   
organophosphate ester transmembrane transporter activity +   
oxidative phosphorylation uncoupler activity  
Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
passive transmembrane transporter activity +   
peptide transmembrane transporter activity +   
poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity 
polyamine transmembrane transporter activity +   
polyol transmembrane transporter activity +   
pyridoxine transmembrane transporter activity 
salt transmembrane transporter activity +   
siderophore-iron transmembrane transporter activity +   
sulfur compound transmembrane transporter activity +   
toxin transmembrane transporter activity +   
vitamin transmembrane transporter activity +   
xenobiotic transmembrane transporter activity +   

Synonyms
Narrow Synonyms: mitochondrial uncoupling protein activity ;   uncoupling protein activity
Alternate IDs: GO:0015302
Definition Sources: PMID:15738989, PMID:16179945

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