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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
catalytic activity +     
catalytic activity, acting on a nucleic acid +   
catalytic activity, acting on a protein +   
cyclase activity +   
deacylase activity +   
demethylase activity +   
glycogen debranching enzyme activity  
hydrolase activity +   
isomerase activity +   
ligase activity +   
lyase activity +   
non-ribosomal peptide synthetase activity +   
oxidoreductase activity +   
peptidoglycan muralytic activity +   
polyketide synthase activity 
Catalysis of a multistep reaction that produce polyketides through decarboxylative condensation of carboxylic acids. The key chain-building reaction, a C-N bond-forming reaction, involves the generation of the characteristic peptide bond by nucleophilic attack of the amino group of an amino-acyl donor unit covalently bound to a downstream peptidyl carrier protein module (amino acyl-S-PCP) on the acyl group of an upstream electrophilic acyl- or peptidyl acyl-S-PCP chain, catalyzed by a condensation (C) domain. Supplementing these core chain-elongation domains are variable numbers of auxiliary domains that are responsible for modification of the growing polypeptide chain by a small set of iterated reactions including epimerization, N-methylation, and heterocyclization.
transferase activity +   

Synonyms
Related Synonyms: PKS activity
Definition Sources: PMID:10631508

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