Send us a Message



 Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner VCMap
Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
negative regulation of macromolecule biosynthetic process (GO:0010558)
Annotations: Rat: (1586) Mouse: (1613) Human: (1742) Chinchilla: (1258) Bonobo: (1326) Dog: (1518) Squirrel: (1275) Pig: (1507)
Parent Terms Term With Siblings Child Terms
aminoglycan biosynthetic process +   
amyloid precursor protein biosynthetic process +   
amylopectin biosynthetic process  
biotin carboxyl carrier protein biosynthetic process 
cellular macromolecule biosynthetic process +   
cutin biosynthetic process +  
cytochrome biosynthetic process +  
holo-[acyl-carrier-protein] biosynthetic process 
integrin biosynthetic process +   
maintenance of translational fidelity  
MHC class I biosynthetic process +   
MHC class II biosynthetic process +   
negative regulation of alcohol biosynthetic process +   
negative regulation of amylopectin metabolic process +  
negative regulation of austinol biosynthetic process 
negative regulation of cell wall polysaccharide catabolic process +  
negative regulation of cellodextrin metabolic process +  
negative regulation of cellotriose metabolic process +  
negative regulation of cellular biosynthetic process +   
negative regulation of cellulose catabolic process 
negative regulation of collagen biosynthetic process  
negative regulation of cyclodextrin metabolic process +  
negative regulation of DNA metabolic process +   
negative regulation of DNA methylation-dependent heterochromatin assembly  
negative regulation of flavonoid biosynthetic process +  
negative regulation of galactoglucomannan catabolic process 
negative regulation of galactomannan catabolic process 
negative regulation of gene expression +   
negative regulation of glucomannan catabolic process 
negative regulation of glycogen metabolic process +   
negative regulation of lipid biosynthetic process +   
negative regulation of macromolecule biosynthetic process +   
Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
negative regulation of meiotic DNA double-strand break formation +  
negative regulation of olefin biosynthetic process +  
negative regulation of pectin catabolic process 
negative regulation of protein metabolic process +   
negative regulation of raffinose biosynthetic process 
negative regulation of reactive oxygen species biosynthetic process +   
negative regulation of receptor catabolic process +   
negative regulation of receptor internalization +   
negative regulation of receptor recycling  
negative regulation of reductive pentose-phosphate cycle 
negative regulation of RNA metabolic process +   
negative regulation of secondary metabolite biosynthetic process +   
negative regulation of starch metabolic process +  
negative regulation of wax biosynthetic process 
negative regulation of xyloglucan metabolic process +  
neuromelanin biosynthetic process 
nitric-oxide synthase biosynthetic process +   
polysaccharide biosynthetic process +   
positive regulation of macromolecule biosynthetic process +   
prosthetic group biosynthetic process +  
regulation of cellular macromolecule biosynthetic process +   
regulation of cutin biosynthetic process +  
regulation of integrin biosynthetic process +   
regulation of macromolecule biosynthetic process +   
regulation of MHC class I biosynthetic process +   
regulation of MHC class II biosynthetic process +   
regulation of nitric-oxide synthase biosynthetic process +   
regulation of polysaccharide biosynthetic process +   
regulation of RNA biosynthetic process +   
regulation of sphingolipid biosynthetic process +   
regulation of thymidylate synthase biosynthetic process +  
regulation of UDP-glucose catabolic process +   
rhodopsin biosynthetic process 
RNA biosynthetic process +   
thymidylate synthase biosynthetic process +  

Synonyms
Definition Sources: GOC:dph, GOC:tb

paths to the root