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Term:
diphosphate hydrolysis-driven proton transmembrane transporter activity (GO:0009678)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
3-sulfino-L-alanine: proton, glutamate antiporter activity  
acetylcholine:proton antiporter activity  
acridine:proton antiporter activity 
amino acid:monoatomic cation antiporter activity +   
aspartate:glutamate, proton antiporter activity  
ATPase-coupled monoatomic cation transmembrane transporter activity +   
ATPase-coupled transmembrane transporter activity +   
azole:proton antiporter activity +   
benomyl:proton antiporter activity 
bicarbonate:monoatomic anion antiporter activity +   
chloride:proton antiporter activity 
cycloheximide:proton antiporter activity 
cytochrome-c oxidase activity  
decarboxylation-driven active transmembrane transporter activity +  
diphosphate hydrolysis-driven proton transmembrane transporter activity 
Catalysis of the reaction: diphosphate + H+(in) + H2O = 2 H+(out) + 2 phosphate.
folate:monoatomic anion antiporter activity  
gamma-aminobutyric acid:proton antiporter activity  
glutathione-regulated potassium exporter activity 
glycine:proton antiporter activity  
L-alanine:proton antiporter activity 
L-glutamate:proton antiporter activity 
light-driven active monoatomic ion transmembrane transporter activity 
metal cation:monoatomic cation antiporter activity +   
metal cation:proton antiporter activity +   
methyl transfer-driven active transmembrane transporter activity 
monoamine:proton antiporter activity  
NADH dehydrogenase (ubiquinone) activity  
orotate:monoatomic anion antiporter activity 
oxalate:chloride antiporter activity 
oxidoreduction-driven active transmembrane transporter activity +   
P-type proton-exporting transporter activity +   
polyamine:proton antiporter activity  
polyspecific organic cation:proton antiporter activity  
potassium ion uniporter activity 
proton channel activity +   
proton-translocating NAD(P)+ transhydrogenase activity  
proton-transporting ATPase activity, rotational mechanism  
sodium ion uniporter activity 
solute:monoatomic cation symporter activity +   
solute:proton symporter activity +   
sulfate:chloride antiporter activity  
tetracycline:proton antiporter activity 
ubiquinol-cytochrome-c reductase activity  
urate:monoatomic anion antiporter activity 
zinc efflux active transmembrane transporter activity 

Synonyms
Exact Synonyms: PP(i) hydrolysis-driven proton transmembrane transporter activity ;   proton-translocating pyrophosphatase activity
Related Synonyms: H+-exporting diphosphatase ;   hydrogen-translocating pyrophosphatase activity ;   proton-pumping diphosphatase ;   proton-pumping pyrophosphatase ;   pyrophosphate hydrolysis-driven proton transmembrane transporter activity
Xrefs: EC:7.1.3.1 ;   MetaCyc:TRANS-RXN-370 ;   RHEA:13973 ;   TC:3.A.10
Definition Sources: GOC:mtg_transport, Wikipedia:Proton-pumping_pyrophosphatase

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