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Ontology Browser

excinuclease repair complex (GO:0009380)
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Parent Terms Term With Siblings Child Terms
excinuclease repair complex 
Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.
Holliday junction resolvase complex  
mismatch repair complex +   
nonhomologous end joining complex +   
nucleotide-excision repair complex +   
Sad1-Kms1 LINC complex 
Shu complex  
type I site-specific deoxyribonuclease complex 
type II site-specific deoxyribonuclease complex 
type III site-specific deoxyribonuclease complex 
type IV site-specific deoxyribonuclease complex 

Exact Synonyms: UvrABC excinuclease complex ;   excinuclease ABC complex
Definition Sources: GOC:mah, GOC:mlg, PMID:12145219, PMID:15192705

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.