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Ontology Browser
Term:
[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity (GO:0008467)
Annotations: Rat: (7) Mouse: (7) Human: (7) Chinchilla: (4) Bonobo: (7) Dog: (6) Squirrel: (7) Pig: (7) Naked Mole-rat: (5) Green Monkey: (7)
Parent Terms Term With Siblings Child Terms
[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity  
Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity  
[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity  
[heparan sulfate]-glucosamine N-sulfotransferase activity  
heparan sulfate 2-O-sulfotransferase activity  
heparan sulfate 6-O-sulfotransferase activity  

Synonyms
Broad Synonyms: 3'-phosphoadenylyl-sulfate:[heparan sulfate]-glucosamine 3-sulfotransferase
Related Synonyms: 3'-phosphoadenylyl-sulfate:heparin-glucosamine 3-O-sulfotransferase activity ;   3-OST-1 activity ;   glucosaminyl 3-O-sulfotransferase activity ;   heparan sulfate D-glucosaminyl 3-O-sulfotransferase activity ;   heparin-glucosamine 3-O-sulfotransferase activity ;   heparin-glucosamine 3-O-sulphotransferase activity ;   isoform/isozyme 1 (3-OST-1, HS3ST1)
Xrefs: EC:2.8.2.23 ;   MetaCyc:2.8.2.23-RXN ;   reactome:R-HSA-2076383 "HS3ST1 sulfates GlcN at C3 in heparan sulfate" ;   reactome:R-HSA-2076611 "HS3STs sulfate GlcN at C3 in heparan sulfate"
Definition Sources: EC:2.8.2.23

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