obsolete signal transduction downstream of smoothened - Ontology Browser

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Term:

obsolete signal transduction downstream of smoothened (GO:0007227)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)

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obsolete signal transduction downstream of smoothened

OBSOLETE. The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.

Synonyms
Replaced By:	GO:0007224
Definition Sources:	PMID:15057936

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.