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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
protein retention in ER lumen  
The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
SREBP-SCAP complex retention in endoplasmic reticulum  

Synonyms
Broad Synonyms: maintenance of protein location in ER lumen
Definition Sources: ISBN:0716731363, PMID:12972550

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