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Ontology Browser

Term:
post-translational protein targeting to endoplasmic reticulum membrane (GO:0006620)
Annotations: Rat: (19) Mouse: (21) Human: (17) Chinchilla: (11) Bonobo: (20) Dog: (15) Squirrel: (18) Pig: (17) Naked Mole-rat: (18) Green Monkey: (18)
Parent Terms Term With Siblings Child Terms
cotranslational protein targeting to membrane +   
negative regulation of protein targeting to membrane +   
positive regulation of protein targeting to membrane +   
post-translational protein targeting to endoplasmic reticulum membrane +   
The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
protein targeting to vacuolar membrane +   
regulation of protein targeting to membrane +   
SRP-dependent cotranslational protein targeting to membrane +   

Synonyms
Exact Synonyms: SRP-independent endoplasmic reticulum protein-membrane targeting ;   posttranslational endoplasmic reticulum membrane targeting ;   posttranslational endoplasmic reticulum protein-membrane targeting ;   posttranslational protein targeting to ER membrane ;   posttranslational protein targeting to endoplasmic reticulum membrane
Definition Sources: ISBN:0716731363

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