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Ontology Browser

Term:
SRP-dependent cotranslational protein targeting to membrane, translocation (GO:0006616)
Annotations: Rat: (8) Mouse: (10) Human: (8) Chinchilla: (3) Bonobo: (3) Dog: (8) Squirrel: (3) Pig: (7)
Parent Terms Term With Siblings Child Terms
posttranslational protein targeting to membrane, translocation +   
protein import into chloroplast stroma +  
protein import into chloroplast thylakoid membrane 
protein import into mitochondrial intermembrane space  
protein import into mitochondrial matrix  
protein import into peroxisome matrix +   
protein import into peroxisome matrix, translocation  
SRP-dependent cotranslational protein targeting to membrane, docking 
SRP-dependent cotranslational protein targeting to membrane, signal sequence processing 
SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition  
SRP-dependent cotranslational protein targeting to membrane, translocation  
The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.

Synonyms
Exact Synonyms: SRP-dependent cotranslational membrane targeting, translocation ;   SRP-dependent cotranslational protein-membrane targeting, translocation ;   translocation during SRP-dependent cotranslational protein targeting to membrane
Broad Synonyms: ER translocation
Definition Sources: ISBN:0716731363

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