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SRP-dependent cotranslational protein targeting to membrane (GO:0006614)
Annotations: Rat: (16) Mouse: (18) Human: (16) Chinchilla: (5) Bonobo: (5) Dog: (15) Squirrel: (5) Pig: (15)
Parent Terms Term With Siblings Child Terms
posttranslational protein targeting to endoplasmic reticulum membrane +   
SRP-dependent cotranslational protein targeting to membrane +   
The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

Exact Synonyms: SRP-dependent cotranslational membrane targeting ;   SRP-dependent cotranslational protein-membrane targeting
Broad Synonyms: ER translocation
Definition Sources: ISBN:0716731363

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