Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
creatine biosynthetic process (GO:0006601)
Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (2) Bonobo: (2) Dog: (3) Squirrel: (2) Pig: (2)
Parent Terms Term With Siblings Child Terms
(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine 
(R)-mandelate catabolic process to benzoate 
(R)-mevalonic acid biosynthetic process +  
2-dehydro-3-deoxy-D-gluconic acid biosynthetic process 
3,4-dihydroxybenzoate biosynthetic process 
3-(2,3-dihydroxyphenyl)propanoate biosynthetic process 
3-(3-hydroxyphenyl)propanoate biosynthetic process 
4-hydroxyphenylacetate biosynthetic process 
4-hydroxyproline biosynthetic process 
abscisic acid biosynthetic process +  
acetate biosynthetic process +   
aerobactin biosynthetic process 
aldonic acid biosynthetic process +  
amino-acid betaine biosynthetic process +   
bile acid biosynthetic process +   
biotin biosynthetic process 
cellular modified histidine biosynthetic process +  
cinnamic acid biosynthetic process +  
clavulanic acid biosynthetic process 
coenzyme B biosynthetic process 
creatine biosynthetic process  
The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.
cyclic 2,3-bisphospho-D-glycerate biosynthetic process 
dethiobiotin biosynthetic process 
ectoine biosynthetic process 
fatty acid biosynthetic process +   
ferulate biosynthetic process 
folic acid-containing compound biosynthetic process +   
formate biosynthetic process 
galacturonate biosynthetic process +  
gallate biosynthetic process 
glucuronate biosynthetic process +  
glutathione biosynthetic process +   
glycine catabolic process to creatine 
glycolate biosynthetic process +   
glycyrrhetinate biosynthetic process 
hydroxylysine biosynthetic process  
indoleacetic acid biosynthetic process +  
jasmonic acid biosynthetic process +  
kynurenic acid biosynthetic process  
L-dopa biosynthetic process +   
L-pipecolic acid biosynthetic process 
lactate biosynthetic process +   
leukotriene A4 biosynthetic process  
leukotriene B4 biosynthetic process 
lincomycin biosynthetic process 
mandelate biosynthetic process 
methylgallate biosynthetic process 
nicotinate biosynthetic process 
o-orsellinic acid biosynthetic process +  
O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process 
ochratoxin A biosynthetic process 
olivetolic acid biosynthetic process 
p-cumate biosynthetic process 
pantothenate biosynthetic process 
para-aminobenzoic acid biosynthetic process 
penicillin biosynthetic process +  
pentalenolactone biosynthetic process 
peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine +  
peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine 
phaseic acid biosynthetic process 
phosphagen biosynthetic process +   
phosphatidylserine biosynthetic process +   
picolinic acid biosynthetic process  
prenylcysteine biosynthetic process 
pyrrolysine biosynthetic process 
pyruvate biosynthetic process +   
quinate biosynthetic process 
retinoic acid biosynthetic process +   
S-methylmethionine biosynthetic process 
salicylic acid biosynthetic process +  
sarcosine biosynthetic process 
sinapate biosynthetic process 

Synonyms
Exact Synonyms: creatine anabolism ;   creatine biosynthesis ;   creatine formation ;   creatine synthesis
Definition Sources: GOC:mah, MetaCyc:GLYCGREAT-PWY, MetaCyc:PWY-6158

paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.