Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

membrane protein ectodomain proteolysis (GO:0006509)
Annotations: Rat: (47) Mouse: (45) Human: (47) Chinchilla: (42) Bonobo: (42) Dog: (44) Squirrel: (42) Pig: (46)
Parent Terms Term With Siblings Child Terms
membrane protein ectodomain proteolysis +   
The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
membrane protein intracellular domain proteolysis +   
membrane protein proteolysis involved in retrograde protein transport, ER to cytosol  

Exact Synonyms: ectodomain cleavage
Broad Synonyms: ectoderm shedding
Related Synonyms: membrane protein solubilization ;   receptor shedding
Definition Sources: GOC:jl,

paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.