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Ontology Browser

Term:
base-excision repair, AP site formation (GO:0006285)
Annotations: Rat: (5) Mouse: (5) Human: (12) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (5)
Parent Terms Term With Siblings Child Terms
base-excision repair, AP site formation +   
The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.
base-excision repair, base-free sugar-phosphate removal  
base-excision repair, DNA ligation  
base-excision repair, gap-filling  
DNA biosynthetic process +   
DNA catabolic process +   
DNA double-strand break processing +   
DNA excision +   
DNA integration +   
DNA ligation +   
DNA modification +   
DNA protection  
DNA recombination +   
DNA repair +   
DNA replication initiation +   
DNA replication termination +   
DNA replication, Okazaki fragment processing +   
DNA replication, synthesis of RNA primer +   
DNA strand elongation +   
DNA strand resection involved in replication fork processing +   
DNA topological change  
DNA-dependent DNA replication maintenance of fidelity +   
establishment of imprinting at mating-type locus +   
formation of extrachromosomal circular DNA +   
G-quadruplex DNA formation  
gap filling involved in double-strand break repair via nonhomologous end joining 
heteroduplex formation +  
lagging strand initiation 
maintenance of DNA methylation  
maintenance of DNA repeat elements +   
maintenance of imprinting at mating-type locus  
mitochondrial DNA metabolic process +   
negative regulation of base-excision repair 
negative regulation of DNA metabolic process +   
nucleotide-excision repair, DNA gap filling  
plastid DNA metabolic process +  
positive regulation of base-excision repair  
positive regulation of DNA metabolic process +   
programmed DNA elimination +   
R-loop disassembly  
regulation of base-excision repair +   
regulation of DNA metabolic process +   
removal of nonhomologous ends +  
resolution of recombination intermediates +   
strand displacement +   
strand invasion +   
telomere maintenance +   
telomere maintenance via base-excision repair  

Synonyms
Definition Sources: ISBN:0815316194

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