In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
DNA dealkylation involved in DNA repair
DNA ligation involved in DNA repair +
DNA replication proofreading
DNA synthesis involved in DNA repair +
double-strand break repair +
interstrand cross-link repair +
mismatch repair +
mitochondrial DNA repair
negative regulation of DNA repair +
non-photoreactive DNA repair
nucleotide phosphorylation involved in DNA repair
nucleotide-excision repair +
positive regulation of DNA repair +
positive regulation of DNA repair by transcription from RNA polymerase II promoter +