Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
3'-tRNA processing endoribonuclease activity  
apurinic/apyrimidinic endoribonuclease activity 
endoribonuclease activity, cleaving miRNA-paired mRNA  
endoribonuclease activity, cleaving siRNA-paired mRNA  
phosphodiesterase decapping endonuclease activity  
ribonuclease [poly-(U)-specific] activity 
ribonuclease III activity +   
Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
ribonuclease IV activity 
ribonuclease IX activity 
ribonuclease M5 activity 
ribonuclease P activity  
ribonuclease P4 activity 
RNA lariat debranching enzyme activity  
RNA-DNA hybrid ribonuclease activity  

Synonyms
Narrow Synonyms: pre-mRNA 3'-end processing endonuclease
Related Synonyms: RNase III activity ;   ribonuclease 3 activity
Xrefs: EC:3.1.26.3 ;   MetaCyc:3.1.26.3-RXN ;   Reactome:R-HSA-9708292 "DICER1 cleaves tRNA" ;   Reactome:R-HSA-9708408 "DICER1 cleaves tRNA Lys TTT 3 in tRNA:HIV RNA hybrid" ;   Reactome:R-HSA-9820840 "DICER1 hydrolyzes maternal mRNA:lncRNA to yield endosiRNA" ;   reactome:R-HSA-203862 "Dicer cleaves pre-miRNA to yield duplex miRNA" ;   reactome:R-HSA-203893 "Microprocessor complex cleaves pri-miRNA to pre-miRNA" ;   reactome:R-HSA-426464 "Dicer cleaves double-stranded RNA to yield double-stranded siRNA"
Definition Sources: PMID:11157775, PMID:15242644

paths to the root