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Ontology Browser

Term:
RNA-DNA hybrid ribonuclease activity (GO:0004523)
Annotations: Rat: (4) Mouse: (4) Human: (9) Chinchilla: (4) Bonobo: (4) Dog: (4) Squirrel: (4) Pig: (4)
Parent Terms Term With Siblings Child Terms
3'-tRNA processing endoribonuclease activity  
apurinic/apyrimidinic endoribonuclease activity 
endoribonuclease activity, cleaving miRNA-paired mRNA  
endoribonuclease activity, cleaving siRNA-paired mRNA  
phosphodiesterase decapping endonuclease activity  
ribonuclease [poly-(U)-specific] activity 
ribonuclease III activity +   
ribonuclease IV activity 
ribonuclease IX activity 
ribonuclease M5 activity 
ribonuclease P activity  
ribonuclease P4 activity 
RNA lariat debranching enzyme activity  
RNA-DNA hybrid ribonuclease activity  
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.

Synonyms
Exact Synonyms: RNA*DNA hybrid ribonucleotidohydrolase activity ;   RNase H activity ;   calf thymus ribonuclease H activity ;   hybrid nuclease activity ;   hybrid ribonuclease activity ;   hybridase (ribonuclease H) ;   hybridase activity ;   ribonuclease H activity
Narrow Synonyms: RNase H1 activity ;   RNase H2 activity ;   RNase H3 activity ;   endoribonuclease0 H activity ;   ribonuclease H1 activity ;   ribonuclease H2 activity ;   ribonuclease H3 activity
Related Synonyms: endoribonuclease H ;   endoribonuclease H (calf thymus)
Alternate IDs: GO:0004524
Xrefs: EC:3.1.26.4 ;   MetaCyc:3.1.26.4-RXN ;   reactome:R-HSA-164519 "RNase H-mediated cleavage of the RNA strand of the -sssDNA:RNA duplex" ;   reactome:R-HSA-164528 "RNase H-mediated cleavage of the template strand" ;   reactome:R-HSA-173769 "RNase H-mediated digestion of tRNA, 3'PPT and cPPT RNA primers" ;   reactome:R-HSA-182795 "RNase H-mediated degradation of the template strand" ;   reactome:R-HSA-182859 "RNase H-mediated degradation of the RNA strand of the -sssDNA:RNA duplex"
Definition Sources: EC:3.1.26.4

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.