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Term:
Parent Terms Term With Siblings Child Terms
5'-hydroxyl dinucleotide hydrolase activity 
DNA endonuclease activity +   
double-stranded RNA-specific ribonuclease activity +   
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters +   
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters +   
oligoribonucleotidase activity  
ribonuclease E activity  
ribonuclease G activity 
ribonuclease T1 activity 
RNA endonuclease activity +   
Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
RNA exonuclease activity +   
rRNA endonuclease activity 
tRNA-specific ribonuclease activity +   

Synonyms
Exact Synonyms: endoribonuclease activity
Related Synonyms: endonuclease G activity
Xrefs: Reactome:R-HSA-9708327 "ANG cleaves tRNA to yield tRNA halves" ;   Reactome:R-HSA-9708812 "ELAC2 cleaves pre-tRNA to yield 3' trailer (type II tRF or tRF-1)" ;   reactome:R-HSA-425923 "IRE1alpha hydrolyzes Xbp1 mRNA and Xbp1 mRNA is spliced" ;   reactome:R-HSA-426520 "Endonucleolytic RISC hydrolyzes target RNAs" ;   reactome:R-HSA-5601887 "PLD6 dimer cleaves primary piRNA transcript to pre-piRNA" ;   reactome:R-HSA-5601910 "Complexed PIWIL2:2'-O-methyl-piRNA cleaves transposon RNA" ;   reactome:R-HSA-6791223 "18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol" ;   reactome:R-HSA-6814555 "Integrator complex processes the 3' end of snRNA" ;   reactome:R-HSA-9009936 "RNASEL cleaves cellular ssRNA" ;   reactome:R-HSA-9009941 "RNASEL cleaves viral ssRNA" ;   reactome:R-HSA-9023909 "C3PO hydrolyzes cleaved passenger strand" ;   reactome:R-HSA-9023912 "AGO2 cleaves passenger strand of duplex siRNA" ;   reactome:R-HSA-927836 "SMG6 hydrolyzes mRNA with premature termination codon"
Definition Sources: GOC:mah, ISBN:0198547684

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