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Ontology Browser

Parent Terms Term With Siblings Child Terms
nuclease activity +     
deoxyribonuclease activity +   
endonuclease activity +   
Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
exonuclease activity +   
oligonucleotidase activity +   
ribonuclease activity +   

Xrefs: reactome:R-HSA-5358512 "MLH1:PMS2 makes single strand incision near insertion/deletion loop of 2 bases or more" ;   reactome:R-HSA-5358518 "MLH1:PMS2 makes single strand incision near 1-2 base mismatch" ;   reactome:R-HSA-5690990 "5'- incision of DNA by ERCC1:ERCC4 in GG-NER" ;   reactome:R-HSA-5693533 "DCLRE1C (ARTEMIS) processes DNA DSB ends" ;   reactome:R-HSA-72180 "Cleavage of mRNA at the 3'-end"
Definition Sources: GOC:mah, ISBN:0198547684

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.