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2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity 
2-dehydro-3-deoxy-D-gluconate aldolase activity 
2-dehydro-3-deoxy-D-pentonate aldolase activity 
2-dehydro-3-deoxy-L-pentonate aldolase activity 
2-dehydro-3-deoxy-phosphogluconate aldolase activity 
2-dehydro-3-deoxyglucarate aldolase activity 
2-dehydropantoate aldolase activity 
2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity 
2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity 
2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity 
2-hydroxyacyl-CoA lyase activity +   
2-keto-3-deoxy-L-rhamnonate aldolase activity 
3-deoxy-D-manno-octulosonate aldolase activity 
4-hydroxy-2-ketopimelate aldolase activity 
4-hydroxy-2-oxoglutarate aldolase activity  
4-hydroxy-L-threonine aldolase activity 
5-dehydro-2-deoxyphosphogluconate aldolase activity 
6-deoxy-6-sulfofructose-1-phosphate aldolase activity 
7,8-dihydromonapterin aldolase activity 
benzoin aldolase activity 
D-threonine aldolase activity 
deoxyribose-phosphate aldolase activity  
dihydroneopterin aldolase activity 
dimethylaniline-N-oxide aldolase activity 
fructose 6-phosphate aldolase activity  
fructose-1-phosphate aldolase activity  
fructose-6-phosphate phosphoketolase activity 
fructose-bisphosphate aldolase activity  
Catalysis of the reaction: beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate.
fucosterol-epoxide lyase activity 
hexulose-6-phosphate synthase activity 
hydroxynitrilase activity +  
indole-3-glycerol-phosphate lyase activity 
ketotetrose-phosphate aldolase activity 
L-fuculose-phosphate aldolase activity 
lactate aldolase activity 
mandelonitrile lyase activity 
phenylserine aldolase activity 
phosphoketolase activity 
propioin synthase activity 
rhamnulose-1-phosphate aldolase activity 
sphinganine-1-phosphate aldolase activity  
tagatose-bisphosphate aldolase activity 
threonine aldolase activity +   
trimethylamine-oxide aldolase activity 
vanillin synthase activity 

Synonyms
Broad Synonyms: aldolase activity
Related Synonyms: 1,6-diphosphofructose aldolase activity ;   D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase (glycerone-phosphate-forming) ;   D-fructose-1,6-bisphosphate D-glyceraldehyde-3-phosphate-lyase activity ;   SMALDO ;   diphosphofructose aldolase activity ;   fructoaldolase activity ;   fructose 1,6-diphosphate aldolase activity ;   fructose 1-monophosphate aldolase activity ;   fructose 1-phosphate aldolase activity ;   fructose diphosphate aldolase activity ;   fructose-1,6-bisphosphate triosephosphate-lyase activity ;   ketose 1-phosphate aldolase activity ;   phosphofructoaldolase activity ;   zymohexase activity
Xrefs: EC:4.1.2.13 ;   MetaCyc:F16ALDOLASE-RXN ;   RHEA:14729 ;   Reactome:R-HSA-71495 "Aldolase tetramers convert GA3P and DHAP to F1,6PP" ;   reactome:R-HSA-71496 "D-fructose 1,6-bisphosphate <=> dihydroxyacetone phosphate + D-glyceraldehyde 3-phosphate"
Definition Sources: EC:4.1.2.13

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