Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

Ontology Browser

Term:
ferrochelatase activity (GO:0004325)
Annotations: Rat: (1) Mouse: (1) Human: (1) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1)
Parent Terms Term With Siblings Child Terms
lyase activity +     
3'-deoxyribose phosphate lyase activity 
alkylmercury lyase activity 
carbon phosphorus lyase activity +  
carbon-carbon lyase activity +   
carbon-halide lyase activity +  
carbon-nitrogen lyase activity +   
carbon-oxygen lyase activity +   
carbon-sulfur lyase activity +   
ferrochelatase activity +   
Catalysis of the reaction: heme B (protoheme) + H+ = Fe(2+) + protoporphyrin IX.
indoleacetaldoxime dehydratase activity 
phosphorus-oxygen lyase activity +   
sirohydrochlorin cobaltochelatase activity 

Synonyms
Related Synonyms: ferro-protoporphyrin chelatase activity ;   heme synthase activity ;   heme synthetase activity ;   iron chelatase activity ;   protoheme ferro-lyase (protoporphyrin-forming) ;   protoheme ferro-lyase activity ;   protoheme ferrolyase activity
Xrefs: EC:4.99.1.1 ;   KEGG_REACTION:R00310 ;   MetaCyc:PROTOHEMEFERROCHELAT-RXN ;   RHEA:22584 ;   reactome:R-HSA-189465 "FECH binds Fe2+ to PRIN9 to form heme"
Definition Sources: RHEA:22584

paths to the root