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Term:
cytochrome-c oxidase activity
(GO:0004129)
Annotations:
Rat: (10)
Mouse: (7)
Human: (15)
Chinchilla: (4)
Bonobo: (7)
Dog: (7)
Squirrel: (8)
Pig: (7)
Naked Mole-rat: (7)
Green Monkey: (7)
Parent Terms
Term With Siblings
Child Terms
active monoatomic ion transmembrane transporter activity
+
electron transfer activity
+
oxidoreductase activity, acting on a heme group of donors
+
oxidoreduction-driven active transmembrane transporter activity
+
proton transmembrane transporter activity
+
3-sulfino-L-alanine: proton, glutamate antiporter activity
acetylcholine:proton antiporter activity
acridine:proton antiporter activity
amino acid:monoatomic cation antiporter activity
+
aspartate:glutamate, proton antiporter activity
ATPase-coupled monoatomic cation transmembrane transporter activity
+
azole:proton antiporter activity
+
benomyl:proton antiporter activity
bicarbonate:monoatomic anion antiporter activity
+
chloride:proton antiporter activity
cycloheximide:proton antiporter activity
cytochrome bo3 ubiquinol oxidase activity
cytochrome-c oxidase activity
Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
diphosphate hydrolysis-driven proton transmembrane transporter activity
electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity
electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity
electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity
electron-transferring-flavoprotein dehydrogenase activity
folate:monoatomic anion antiporter activity
gamma-aminobutyric acid:proton antiporter activity
glutathione-regulated potassium exporter activity
glycine:proton antiporter activity
iron-cytochrome-c reductase activity
L-alanine:proton antiporter activity
L-glutamate:proton antiporter activity
light-driven active monoatomic ion transmembrane transporter activity
metal cation:monoatomic cation antiporter activity
+
metal cation:proton antiporter activity
+
monoamine:proton antiporter activity
NADH dehydrogenase (ubiquinone) activity
nitric oxide dioxygenase activity, heme protein as donor
orotate:monoatomic anion antiporter activity
oxalate:chloride antiporter activity
oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor
+
P-type proton-exporting transporter activity
+
plastoquinol--plastocyanin reductase activity
polyamine:proton antiporter activity
polyspecific organic cation:proton antiporter activity
potassium ion uniporter activity
proton channel activity
+
proton-translocating NAD(P)+ transhydrogenase activity
proton-transporting ATPase activity, rotational mechanism
sodium ion uniporter activity
solute:monoatomic cation symporter activity
+
solute:proton symporter activity
+
sulfate:chloride antiporter activity
tetracycline:proton antiporter activity
transmembrane ascorbate ferrireductase activity
ubiquinol-cytochrome-c reductase activity
urate:monoatomic anion antiporter activity
zinc efflux active transmembrane transporter activity
Synonyms
Narrow Synonyms:
aa3-type cytochrome c oxidase ; ba3-type cytochrome c oxidase ; caa3-type cytochrome c oxidase ; cbb3-type cytochrome c oxidase ; cytochrome a3 activity ; cytochrome aa3 activity ; indophenol oxidase ; indophenolase
Related Synonyms:
complex IV (mitochondrial electron transport) activity ; cytochrome oxidase activity ; warburg's respiratory enzyme activity
Xrefs:
EC:7.1.1.9 ; MetaCyc:CYTOCHROME-C-OXIDASE-RXN ; RHEA:11436 ; reactome:R-HSA-163214 "Electron transfer from reduced cytochrome c to molecular oxygen"
Definition Sources:
RHEA:11436