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Ontology Browser
Term:
N-acetylgalactosamine-4-sulfatase activity (GO:0003943)
Annotations: Rat: (1) Mouse: (1) Human: (2) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
arylsulfatase activity  
cellulose-polysulfatase activity 
cerebroside-sulfatase activity  
choline-sulfatase activity 
chondro-4-sulfatase activity 
chondro-6-sulfatase activity 
D-lactate-2-sulfatase activity 
disulfoglucosamine-6-sulfatase activity 
endosulfan hemisulfate sulfatase activity 
endosulfan sulfate hydrolase activity 
glucuronate-2-sulfatase activity  
glycosulfatase activity 
iduronate-2-sulfatase activity  
linear primary-alkylsulfatase activity 
monomethyl-sulfatase activity 
N-acetylgalactosamine-4-sulfatase activity  
Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.
N-acetylgalactosamine-6-sulfatase activity  
N-acetylglucosamine-6-sulfatase activity  
N-sulfoglucosamine-3-sulfatase activity  
steryl-sulfatase activity  

Synonyms
Exact Synonyms: N-acetylgalactosamine-4-sulphatase activity ;   arylsulfatase B
Broad Synonyms: chondroitinsulfatase
Related Synonyms: N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase activity ;   N-acetylgalactosamine 4-sulfate sulfohydrolase activity ;   acetylgalactosamine 4-sulfatase activity
Xrefs: EC:3.1.6.12 ;   MetaCyc:3.1.6.12-RXN ;   Reactome:R-HSA-2282889 "Defective ARSB does not hydrolyse C4S/C6S chains" ;   Reactome:R-HSA-9036065 "Defective ARSB does not hydrolyse DS" ;   Wikipedia:Arylsulfatase_B ;   reactome:R-HSA-1606789 "ARSB hydrolyses DS" ;   reactome:R-HSA-1793207 "ARSB hydrolyses C4S/C6S chains"
Definition Sources: EC:3.1.6.12

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