Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
DNA-(apurinic or apyrimidinic site) endonuclease activity +
DNA-deoxyinosine glycosylase activity
DNA-methyltransferase activity +
eoxin A4 synthase activity
hepoxilin A3 synthase activity
hexulose-6-phosphate isomerase activity
integrase activity +
intramolecular lyase activity +
intramolecular oxidoreductase activity +
intramolecular transferase activity +
peroxynitrite isomerase activity
phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands