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Ontology Browser

DNA clamp loader activity (GO:0003689)
Annotations: Rat: (9) Mouse: (9) Human: (9) Chinchilla: (9) Bonobo: (9) Dog: (8) Squirrel: (0) Pig: (8)
Parent Terms Term With Siblings Child Terms
bent DNA binding  
chromatin DNA binding +   
damaged DNA binding +   
DNA binding, bending +   
DNA clamp loader activity  
Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
DNA clamp unloader activity  
DNA end binding  
DNA secondary structure binding +   
DNA template activity +   
double-stranded DNA binding +   
flap-structured DNA binding +   
G-quadruplex DNA binding +   
histone-dependent DNA binding  
random coil DNA binding 
recombination hotspot binding  
sequence-specific DNA binding +   
single-stranded DNA binding +   
transcription regulatory region DNA binding +   
triplex DNA binding  

Exact Synonyms: DNA clamp loading ATPase activity
Narrow Synonyms: PCNA loading activity ;   PCNA loading complex activity
Xrefs: reactome:R-HSA-176264 "Recruitment of the Rad9-Hus1-Rad1 complex to DNA"
Definition Sources: GOC:mah, GOC:vw, PMID:16082778

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.