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Ontology Browser

Term:
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (GO:0002489)
Annotations: Rat: (2) Mouse: (2) Human: (2) Chinchilla: (1) Bonobo: (2) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent  
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent 

Synonyms
Exact Synonyms: TAP-dependent endogenous peptide antigen processing and presentation via MHC class Ib via ER pathway
Definition Sources: GOC:add, PMID:15928678

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