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Ontology Browser

Term:
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (GO:0002480)
Annotations: Rat: (0) Mouse: (0) Human: (1) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent  
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.

Synonyms
Exact Synonyms: TAP-independent exogenous peptide antigen processing and presentation via MHC class I
Broad Synonyms: cross presentation
Definition Sources: GOC:add, PMID:15224093, PMID:15771591, PMID:16181335

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