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Ontology Browser

Term:
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479)
Annotations: Rat: (1) Mouse: (1) Human: (2) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent  
The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent  

Synonyms
Exact Synonyms: TAP-dependent exogenous peptide antigen processing and presentation via MHC class I
Broad Synonyms: cross presentation
Definition Sources: GOC:add, PMID:15224093, PMID:15771591, PMID:16181335

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