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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
kinin cascade +     
negative regulation of kinin cascade +  
plasma kallikrein-kinin cascade +   
positive regulation of kinin cascade +  
regulation of kinin cascade +  
tissue kallikrein-kinin cascade +   
A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.

Synonyms
Exact Synonyms: glandular kallikrein-kinin cascade
Definition Sources: GOC:add, PMID:11842287, PMID:14501145

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