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Ontology Browser

Term:
desensitization of G protein-coupled receptor signaling pathway (GO:0002029)
Annotations: Rat: (30) Mouse: (29) Human: (26) Chinchilla: (22) Bonobo: (24) Dog: (11) Squirrel: (0) Pig: (12)
Parent Terms Term With Siblings Child Terms
adaptation to pheromone regulating conjugation with mutual genetic exchange 
desensitization of G protein-coupled receptor signaling pathway +   
The process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway after prolonged stimulation with an agonist of the pathway.
G protein-coupled receptor catabolic process  
negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation 
negative regulation of adenosine receptor signaling pathway  
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway +   
negative regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process  
negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway 
negative regulation of angiotensin-activated signaling pathway 
negative regulation of beta1-adrenergic receptor activity 
negative regulation of octopamine or tyramine signaling pathway +  
negative regulation of opioid receptor signaling pathway +  
negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway +   
negative regulation of proteinase activated receptor activity 
negative regulation of thrombin-activated receptor signaling pathway  
suppression by symbiont of host G protein-coupled receptor signal transduction 
termination of G protein-coupled receptor signaling pathway  

Synonyms
Exact Synonyms: desensitisation of G-protein coupled receptor protein signalling pathway ;   desensitization of G-protein coupled receptor protein signaling pathway
Definition Sources: PMID:8396717

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.