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Ontology Browser

Term:
aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway (GO:0000952)
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Parent Terms Term With Siblings Child Terms
anthranilate catabolic process 
aromatic amino acid family catabolic process to alcohol via Ehrlich pathway 
aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway 
The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway 
L-phenylalanine catabolic process +   
methionine catabolic process to 3-methylthiopropanoate 
tryptophan catabolic process +   
tyrosine catabolic process +   

Synonyms
Definition Sources: GOC:krc, PMID:18281432

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.