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Ontology Browser

Term:
nuclear MIS12/MIND complex (GO:0000818)
Annotations: Rat: (3) Mouse: (3) Human: (4) Chinchilla: (0) Bonobo: (0) Dog: (5) Squirrel: (0) Pig: (3)
Parent Terms Term With Siblings Child Terms
COMA complex 
condensed nuclear chromosome inner kinetochore  
condensed nuclear chromosome outer kinetochore +   
nuclear MIS12/MIND complex  
A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.

Synonyms
Exact Synonyms: MIND complex ;   Mtw1p Including Nnf1p-Nsl1p-Dsn1p complex
Definition Sources: GOC:krc, GOC:se, PMID:14633972

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.