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Ontology Browser

Term:
Parent Terms Term With Siblings Child Terms
peptidase complex +     
SAGA-type complex +     
ADA complex 
ATAC complex  
endopeptidase complex +   
glutathione hydrolase complex 
H-gal-GP complex 
m-AAA complex  
PNGase complex 
SAGA complex  
A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
serine-type peptidase complex +   
signal peptidase complex  
SLIK (SAGA-like) complex  
transcription factor TFTC complex  

Synonyms
Exact Synonyms: Spt-Ada-Gcn5-acetyltransferase complex
Narrow Synonyms: PCAF complex ;   PCAF histone acetylase-associated complex ;   SPT3-TAF9-PCAF acetylase complex
Related Synonyms: SPT3-TAF9-GCN5 acetylase complex ;   STAGA coactivator complex ;   STAGA complex
Alternate IDs: GO:0000125 ;   GO:0030914
Definition Sources: PMID:10637607, PMID:17337012, PMID:19056896, PMID:20838651, PMID:33004486

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