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Ontology Browser

Term:
negative regulation of canonical NF-kappaB signal transduction (GO:0043124)
Annotations: Rat: (75) Mouse: (81) Human: (82) Chinchilla: (59) Bonobo: (68) Dog: (78) Squirrel: (64) Pig: (77) Naked Mole-rat: (58) Green Monkey: (67)
Parent Terms Term With Siblings Child Terms
I-kappaB phosphorylation +   
negative regulation of calcium-mediated signaling +   
negative regulation of cAMP-mediated signaling  
negative regulation of cAMP/PKA signal transduction  
negative regulation of canonical NF-kappaB signal transduction  
Any process that stops, prevents, or reduces the frequency, rate or extent of a canonical NF-kappaB signaling cascade.
negative regulation of cell cycle checkpoint +   
negative regulation of cGMP-mediated signaling +   
negative regulation of cytoplasmic pattern recognition receptor signaling pathway +   
negative regulation of endoplasmic reticulum unfolded protein response +   
negative regulation of hippo signaling  
negative regulation of hypoxia-inducible factor-1alpha signaling pathway  
negative regulation of intracellular steroid hormone receptor signaling pathway +   
negative regulation of intrinsic apoptotic signaling pathway +   
negative regulation of MAPK cascade +   
negative regulation of nitric oxide mediated signal transduction +   
negative regulation of non-canonical NF-kappaB signal transduction  
negative regulation of peroxisome proliferator activated receptor signaling pathway  
negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  
negative regulation of phospholipase C/protein kinase C signal transduction  
negative regulation of phosphorelay signal transduction system +  
negative regulation of protein kinase C signaling  
negative regulation of retinoic acid receptor signaling pathway  
negative regulation of signal transduction by p53 class mediator +   
negative regulation of SMAD protein signal transduction  
negative regulation of small GTPase mediated signal transduction +   
negative regulation of SREBP signaling pathway +   
negative regulation of stress-activated protein kinase signaling cascade +   
negative regulation of thyroid hormone receptor signaling pathway 
negative regulation of TOR signaling +   
negative regulation of vitamin D receptor signaling pathway  
positive regulation of canonical NF-kappaB signal transduction  
regulation of canonical NF-kappaB signal transduction +   

Synonyms
Exact Synonyms: negative regulation of I-kappaB kinase/NF-kappaB signaling
Narrow Synonyms: inhibition of I-kappaB kinase/NF-kappaB cascade
Related Synonyms: down regulation of I-kappaB kinase/NF-kappaB cascade ;   downregulation of I-kappaB kinase/NF-kappaB cascade ;   negative regulation of I-kappaB kinase/NF-kappaB cascade
Definition Sources: GOC:jl

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